International Research journal of Management Science and Technology

  ISSN 2250 - 1959 (online) ISSN 2348 - 9367 (Print) New DOI : 10.32804/IRJMST

Impact Factor* - 6.2311


**Need Help in Content editing, Data Analysis.

Research Gateway

Adv For Editing Content

   No of Download : 17    Submit Your Rating     Cite This   Download        Certificate

SOCIAL-COGNITIVE AND DEMOGRAPHIC CORRELATES OF MEDICATION ADHERENCE TO ANTIRETROVIRAL THERAPY (ART) IN PERSONS INFECTED WITH HIV

    1 Author(s):  DR RAZI FARAZ KHAN

Vol -  8, Issue- 1 ,         Page(s) : 200 - 207  (2017 ) DOI : https://doi.org/10.32804/IRJMST

Abstract

Medication-taking is an essential component of self-management in HIV/AIDS. Antiretroviral therapy (ART) is a key component of improving health outcomes of HIV-positive individuals. Antiretroviral therapy is the combination of drugs designed to inhibit the proliferation of HIV, improve the patient’s immunological status, and prolong life. The term ‘medication adherence’ in HIV/AIDS care specifically refers to the ability of the person living with HIV/AIDS to be involved in choosing, starting, managing and maintaining a given therapeutic combination medication regimen to control viral (HIV) replication and improve immune function. Determinants of adherence : complexity and duration of treatment, characteristics of the illness, iatrogenic effects of treatment, costs of treatment, characteristics of health service provision, interaction between practitioner and patient, and socio-demographic variables. These serve as helpful heuristic both for understanding non-adherence and for addressing it.

  1. Bandura A (1997). Self-Efficacy: The Exercise of Control. W.H. Freeman & Company, New York, NY, USA.
  2. Bandura A. Human agency in social cognitive theory. American Psychologist. 1989;44(9):1175–1184. [PubMed).
  3. Bandura A. Self efficacy. In: Ramachaudran VS, editor.Encyclopedia of human behavior. Vol. 4. Academic Press; New York: 1994. pp. 71–81. Reprinted in H. Friedman [Ed.], Encyclopedia of mental health. San Diego: Academic Press, 1998.
  4. Bandura A: Health promotion by social cognitive means. Health Educ Behav 2004, 31:143-164
  5. Bangsberg, D.R. (2006). Less than 95% adherence to nonnucleoside reversetranscriptase inhibitor therapy can lead to viral suppression. Clinical Infectious Diseases, 43(7), 939-941.
  6. Bangsberg, D.R., Perry, S., Charlebois, E.D., Clark, R.A,, Roberston, M., Zolopa, A.R., & Moss, A. (2001).  Non-adherence to highly active antiretroviral therapy predicts progression to AIDS. AIDS, 15(9), 1181-1183.
  7. Baron, R. M. & Kenny, D. A. (1986). The moderator-mediator variable distinction in social
  8. psychological research: Conceptual, strategic and statistical considerations. Journal of
  9. Personality and Social Psychology, 51, 1173-1182
  10. Barroso, J., & Sandelowski, M. (2001). In the field with the Beck Depression Inventory. Qualitative Health Research, 11(4), 491-504.
  11. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Archives of General Psychiatry. 1961;4(Jun):561–571. [PubMed]
  12. Beck, A., Steer, R. A, Brown, G. K. (1996). BDI-II Manual. San Antonio: The Psychological Corporation, Harcourt Brace & Company.
  13. Berger, B. E., Ferrans, C. E., & Lashley, F. R. (2001). Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Research on Nursing Health, 24, 518-529. 
  14. Berger-Greenstein, J. A., Cuevas, C. A., Brady, S. M., Trezza, G., Richardson, M. A., & Keane, T. M. (2007). Major depression in patients with HIV/AIDS and substance abuse. AIDS Patient Care and STDs, 21(12), 942-955.
  15. C.A.T. Pinheiro, J.C. de-Carvalho-Leite, M.L. Drachler and V.L. Silveira(2002) Factors associated with adherence to antiretroviral therapy in HIV/AIDS patients: a cross-sectional study in Southern Brazil. Braz J Med Biol Res,  Volume 35(10) 1173-1181.Retrived on 1 jan 2014 from http://dx.doi.org/10.1590/S0100-879X2002001000010 
  16. Cha, E., Erlen, J. A., Kim, K. H., Sereika, S. M., & Caruthers, D. (2007). Mediating roles of medication–taking self-efficacy and depressive symptoms on self-reported medication adherence in persons with HIV: A questionnaire survey. International Journal of Nursing Studies, doi:10.1016/j.ijnurstu.2007.08.003.
  17. Chesney MA, Ickovics JR, Chambers DB, Gifford AL, Neidig J, Zwickl B & Wu AW (2000). Self-reported adherence to antiretroviral medication among participants in HIV clinical trials; the AACTG Adherence Instruments. AIDS Care, 12: 255-266.        [ Links ]
  18. Chesney MA, Ickovics JR, Chambers DB, Gifford AL, Neidig J, Zwickl B & Wu AW (2000). Self-reported adherence to antiretroviral medication among participants in HIV clinical trials; the AACTG Adherence Instruments. AIDS Care, 12: 255-266
  19. Costa PT Jr, McCrae RR (1992) Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) professional manual. Odessa, Fl: Psychological Assessment Resources.
  20. Costa, P., McCrae, RR. (1992). Revised NEO Personality Inventory (NEO-PI-R) and NEO Five- Factor Inventory (NEO-FFI): Professional manual. Odessa, FL: Psychological Assessment Resources. 
  21. Costa, R. R., & McCrae, P. T. (1999). A Five Factor Theory of Personality. In L. A. Pervin & O. P. John (Eds.), Handbook of personality: Theory and research (pp. 139-153). New York: Guilford Press.
  22. DiMatteo, M.R. (2004). Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Medical Care, 42(3), 200-209.
  23. DiMatteo, M.R.,  & DiNicola, D.D. (1982). Achieving patient compliance. New York, Pergamon.
  24. DiMatteo, M.R.,  Lepper, H.S.,  & Croghan, T.W. (2000). Depression is a risk factor for noncompliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence. Archives of Internal Medicine, 160, 2101–2107.
  25. Eldred LJ, Wu AW, Chaisson RE & Moore RD (1998). Adherence to antiretroviral and Pneumocystisprophylaxis in HIV disease. Journal of Acquired Immune Deficiency Syndrome, 18: 117-125.
  26. Farmer, K.C. (1999). Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clinical Therapeutics,21, 1074–1090.
  27. Gordillo V, Del Amo J, Soriano V & Gonzalez-Lahoz J (1999). Sociodemographic and psychological variables influencing adherence to antiretroviral therapy. AIDS, 13: 1763-1769.        [ Links ]
  28. Haubrich RH, Little SJ, Currier JS, Forthal DN, Kemper CA, Beall GN, Johnson D, Dube MP, Hwang JY & McCutchan JA (1999). The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response. AIDS, 13: 1099-1107.        
  29. Haynes, R.B. (2001). Interventions for helping patients to follow prescriptions for medications. Cochrane Database of Systematic Reviews, Issue 1.
  30. Heaney, C.A., & Israel, B.A. (2008). "Social networks and social support". In Glanz, K., Rimer, B.K., & Viswanath, K.Health Behavior and Health Education: Theory, Research, and Herek, G. M., Mitnick, L., Burris, S., Chesney, M., Devine, P., Fullilove, M. T., Fullilove, R., Gunther, H. C., Levi, J., Michaels, S., Novick, A., Pryor, J., Snyder, M., & Sweeney, T. (1998). AIDS and stigma: A conceptual framework and research agenda. AIDS and Public Policy Journal, 13(1), 36-47.Practice (4th ed.). San Francisco, CA: Jossey-Bass.
  31. Laine, C. et al. (2000). Adherence to antiretroviral therapy by pregnant women infected with human immunodeficiency virus: A pharmacy claims-based analysis. Obstetrics & Gynecology,  95, 167-173.
  32. Lerner, B. H. (1997) From careless consumptives to recalcitrant patients: the historical construction of nonadherence. Social Science & Medicine, (45), 1423-1431.
  33. Murphy DA, Greenwell L, Hoffman D. Factors associated with antiretroviral adherence among HIV-infected women with children. Women Health. 2002;36(1):97–111. [PubMed].
  34. Murphy DA, Stein JA, Schlenger W, Maibach E. Conceptualizing the multidimensional nature of self efficacy: assessment of situational context and level of behavioral challenge to maintain safer sex: National Institute of Mental Health Multisite HIV Prevention Trial Group. Health Psychology. 2001;20(4):281–290. [PubMed].
  35. Murphy, D.A., Marelich, W.D., Hoffman, D., & Steers, W.N. (2004). Predictors of antiretroviral adherence. AIDS Care, 16(4), 471-484.
  36. Palella, F.J. Jr, Delaney, K.M., Moorman, A.C., Loveless, M.O., Fuhrer, J., Satten, G.A., Aschman, D.J., & Holmberg, S.D. (1998). Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. New England Journal of Medicine, 338, (13), 853-860.
  37. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, Wagener MM & Singh N (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133: 21-30
  38. Quinn, T.C., Wawer, M.J., Sewankambo, N., Serwadda, D., Li, C., Wabwire-Mangen, F., Meehan, M.O., Lutalo, T., & Gray, R.H. (2000). Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. New England Journal of Medicine, 342(13), 921-929.
  39. Sethi, A.K., Celentano, D.D., Gange, S.J., Moore, R.D., & Gallant, J.E. (2003). Association between adherence to antiretroviral therapy and human immunodeficiency virus drug resistance. Clinical Infectious Diseases, 37(8), 1112-1118.
  40. Stein, M.D. et al. (2000). Adherence to antiretroviral therapy among HIV-infected methadone patients: effect of ongoing illicit drug use. American Journal of Drug & Alcohol Abuse,26, 195-205.

*Contents are provided by Authors of articles. Please contact us if you having any query.






Bank Details